RALEIGH A new approach to designing anti-cancer drugs developed by researchers at N.C. State University and UNC-Chapel Hill shows just how complex the products of the rapidly emerging field of engineered drug therapies can be.
The nanoparticle they created is essentially a tiny machine that performs a sequence of tasks in a pre-set, specific order to overcome cancer cells. It persuades a cancer cell to latch onto it, then it uses first one method, then another to kill the cells.
They are programmed almost like a computer so that they tackle the problem step by step, said Zhen Gu, senior author of a paper on the research and an assistant professor in the joint biomedical engineering program at both universities.
The particle isnt exactly a drug itself. Tianyue Jiang, a lead author of the paper who works in Gus lab, calls it a drug delivery vehicle.
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