The Columbus State women can move into second place in the Peach Belt Conference Western Division standings with a win Wednesday night at Young Harris.
The Lady Cougars, who won two straight at home last weekend against Francis Marion and UNC Pembroke, are tied with Georgia College for third at 4-2.
Young Harris, which has won five straight, is second at 4-1. North Georgia is on top at 5-0.
This will be only the third meeting between CSU and Young Harris, which moved into Division II and joined the PBC last season. The two teams split last season's meetings, each winning on the road.
Young Harris enters Wednesday night's game coming off back-to-back wins over ranked teams. Young Harris beat then-No. 19 Clayton State and No. 22 Georgia College.
Tipoff is set for 5:30 p.m. with the men's game to follow at 7:30.
The CSU men snapped a three-game losing streak with its win Sunday over UNC Pembroke.
The Cougars are tied for fifth place in the West with Georgia College at 2-4. Georgia Southwestern leads at 4-1, followed by Montevallo at 4-2, Young Harris at 3-2 and North Georgia at 2-3.
CSU point guard Jahmad Saleem is doubtful for Wednesday's game due to an ankle injury. Saleem has played in just four games this season after missing the start of the year with a wrist injury.
The Cougars have struggled on the road, losing six straight PBC road game and eight of the last nine.
Young Harris beat CSU in both meetings last season.
The CSU will return home for Saturday games against Armstrong Atlantic.