Two 18-wheelers collided around 4:45 p.m. Tuesday at the intersection of U.S. 431 South and Russell County Road 4 in Pittsview, Ala.
Both drivers appear to have escaped without serious injuries.
About one-quarter of a mile of the southbound lane of U.S. 431 was diverted into the northbound lanes of 431.
Alabama State Troopers and other emergency personnel were still on the scene around 5:30 p.m.
The southbound lane was still blocked and traffic was being diverted into the other lane at 11 p.m. as crews were cleaning up the mess. Lights had been brought in and crews were working to get the overturned truck out of the road.